Jesus' response to His mother at the wedding—'My hour has not yet come'—was not disrespect but perhaps a challenge to attach real faith with mere knowledge.
John Ritenbaugh stresses that unless the splinters of the greater church of God repair their mangled relationships with the Almighty, recoupling will be impossible. A major contributory factor in the scattering is the deceitful heart of man (Jeremiah 17:9). . .
John and James were related, but still had to have the Messiah revealed to them. God is involved in the details of our lives as well as the great events in history.