Genesis 49 and Deuteronomy 33 identify the family traits of the Israelite tribes. God maintains a closer relationship with Israel than with any other people.
God frequently bypasses the firstborn, selecting for His purposes another sibling. Jacob selected Joseph's second son, Ephraim, to receive the blessing.
No matter how scattered Israel is, God will not lose the smallest grain. Using Jerusalem as a reference point, Israel dispersed north and west into Europe.
Those who follow Christ are the true Israel, the Elect, and the Chosen, called by God to precede unfaithful physical Israel in the salvation process.