The chief priests, scribes, and elders, along with Judas, conspired to assassinate Jesus Christ. These men, part of the Sanhedrin, were motivated by envy of Jesus' spiritual power and His popularity and acceptance by the people. As early as John 5:18, they were plotting to kill Him, seeking justification for their actions by wrongly believing He was sinning. Matthew 26:3-5 indicates that their conspiracy continued until two days before Jesus' crucifixion, as they aimed to carry out their plan without tarnishing their reputation or lives. The conspiracy against Jesus involved three major elements: a common purpose among the conspirators to prevent loss of power, authority, income, or social status; a belief that their cause was righteous, justifying their actions; and personal gain as a result of their plot's success. Judas, whose motivations are not clearly stated, was bribed to participate in the conspiracy.

The conspiracy against Jesus Christ began early in His life, as people started to plot against Him. In Luke 22, Satan entered Judas, leading him to conspire with the priests to deliver Jesus into their hands, allowing them to put Him to death. This act of conspiracy was driven by self-interest and the influence of Satan, who seeks to destroy anything connected with God's purpose. The Scriptures show that conspiracies against Jesus were motivated by the desire for power and control, reflecting the broader pattern of human nature influenced by Satan's spirit.

Jesus Christ faced conspiracies throughout His ministry. After healing on the Sabbath, a conspiracy was formed against Him, as noted in Mark, where the term "plotted" is used synonymously with "conspired." In Matthew 22:15, a milder conspiracy aimed to trap Jesus in His words, though not necessarily to kill Him. A more severe plot against His life is described in Matthew, where a conference was held to plan His death. Another conspiracy occurred after His resurrection in Matthew 28:12, where efforts were made to conceal the resurrection from the public. Additionally, in Acts 5:33, a conspiracy targeted the early church, and in Acts 9:23, a plot was devised to kill Paul, illustrating the continuation of conspiracies against those associated with Jesus Christ.