Jesus was conceived in the virgin Mary by the Holy Spirit, fulfilling Isaiah 7:14 and 9:6-7. The angel Gabriel convinced Mary by quoting these Messianic prophecies, telling her that God had chosen her to fulfill them. When she asked how she could conceive without knowing a man, he answered in a Hebrew-style parallelism: the Holy Spirit would come upon her, meaning the power of the Highest would overshadow her. The Holy Spirit is thus God's power to effect this miracle. The word "overshadow" recalls God covering the Tabernacle in the wilderness, and it assured Mary of His protection and provision. The angel gave her a sign in her cousin Elizabeth, barren and old, who was six months pregnant. His statement that nothing is impossible with God, more literally that no word from God is powerless, echoes Isaiah 55:11: God's word accomplishes what He pleases. Mary submitted unconditionally, calling herself the Lord's maidservant. The favor she received was God's gracious gift, not a merit that makes her worthy of adoration, and the glory belongs to God. Later, an angel told Joseph in a dream that the child conceived in Mary was of the Holy Spirit, that He would be named Jesus because He would save His people from their sins, and that He fulfilled the prophecy of Immanuel, God with us. Joseph obeyed without complaint and took Mary as his wife. God prepared this humble, thoughtful, submissive couple to raise His Son.

The life of Jesus Christ serves as a perfect example for us to follow in every aspect. Regarding His conception, it is emphasized that He was physically born through the normal process of human birth to the virgin Mary. God the Father caused Mary to conceive by the Holy Spirit, highlighting the miraculous nature of His coming into being. This divine miracle underscores His humanity, as He was born of a woman, flesh and blood, subject to the same terms, forces, and conditions as any other man. Furthermore, scriptures clarify that Jesus Christ was not bound by the Old Covenant rules and regulations from His birth, as some have argued. Instead, He was placed under the law only at the time of His crucifixion, when God the Father laid the burden of the world's sins upon Him. Leading a perfect life, He was not subject to the ceremonial laws designed to remind Israel of their sins and need for a Savior. Therefore, His example remains one that we are to emulate in all respects, walking in His footsteps as true Christians.

The conception of Jesus Christ holds a profound significance in understanding His divine nature and role. As declared in Psalm 2, God proclaimed the begetting of His Son, identifying Jesus of Nazareth as the only begotten Son of God, unique and one of a kind. This declaration, though written centuries earlier, was literally assigned by God the Father at the moment Jesus was born of the virgin Mary, marking the beginning of His human life. Even at conception in Mary's womb, He was God, sharing the same divine essence as the Father, yet also becoming human. At the moment of His birth, He was exalted to a position He had not held before, already qualified as God to fulfill His purpose. Throughout His life and ministry, He performed His role as the New Covenant High Priest, not needing to qualify further, for He was already divine from the womb.

The conception of Jesus Christ, as detailed in the accounts of Luke and Matthew, reveals a profound divine intervention. In Luke 1, the angel Gabriel, sent by God, appears to Mary, a virgin betrothed to Joseph of the house of David, in Nazareth. Gabriel announces that Mary has found favor with God and will conceive a Son, to be named Jesus, who will be great, called the Son of the Most High, and will reign over the house of Jacob forever with a Kingdom that will have no end. Mary, puzzled by this since she has not known a man, is told by Gabriel that the Holy Spirit will come upon her, and the power of the Highest will overshadow her, ensuring the miraculous nature of this conception. This overshadowing is presented as a comforting act, akin to the protective presence of God over the Israelites in the wilderness, assuring Mary that God will handle all aspects of this extraordinary event. In Matthew 1, the narrative continues with Joseph, who, upon discovering Mary's pregnancy, contemplates a quiet resolution to avoid shame. While considering his options, an angel of the Lord, likely Gabriel, appears to him in a dream, confirming that the Child conceived in Mary is of the Holy Spirit. The angel instructs Joseph that this Son will save His people and be called Immanuel, meaning God with us. Joseph, depicted as humble and obedient, accepts this divine message without hesitation and complies with the angel's command. These accounts emphasize the fulfillment of ancient prophecies and the direct involvement of God's power in bringing forth Jesus Christ, underscoring the significance of His conception as a pivotal moment in divine history.

The conception of Jesus Christ is a foundational truth that underscores His role as the Redeemer of humanity. As recorded in Matthew 1:18-21, the birth of Jesus Christ occurred when Mary, betrothed to Joseph, was found with child by the Holy Spirit before they came together. An angel of the Lord appeared to Joseph in a dream, reassuring him not to fear taking Mary as his wife, for that which was conceived in her was of the Holy Spirit. The angel declared that she would bring forth a Son named Jesus, meaning Savior, for He would save His people from their sins. Further, in Luke 1:26-35, the angel Gabriel was sent by God to Mary in Nazareth, announcing that she, a virgin, would conceive in her womb and bring forth a Son named Jesus. Mary, puzzled since she had not known a man, was told that the Holy Spirit would come upon her, and the power of the Highest would overshadow her, making the Holy One to be born the Son of God. This confirms that Jesus was placed in Mary's womb through the Holy Spirit, born as a human yet called the Son of God due to His divine origin. Galatians 4:4-5 emphasizes that when the fullness of time had come, God sent forth His Son, born of a woman, born under the law, to redeem those under the law. This highlights His humanity, being born of a woman, and His purpose to redeem mankind. Additionally, in Matthew 1:23, quoting Isaiah 7:14, it is prophesied that a virgin shall be with child and bear a Son named Immanuel, translated as "God with us," showing His dual nature as both human and divine, born of a woman yet being the Son of God. These accounts collectively affirm that Jesus Christ was conceived through the Holy Spirit in a human woman, Mary, establishing His unique nature as both Son of Man and Son of God, qualifying Him to be the perfect sacrifice for human sin.

Some scholars calculate that Jesus Christ's conception occurred on March 25 based on the timing of Zacharias' temple service and the six-month interval to Jesus Christ's conception. This calculation places Jesus Christ's birth on December 25. However this calculation overlooks the additional weeks required for the holy days of Unleavened Bread Pentecost and Tabernacles. Accounting for these weeks shows that Zacharias' second course occurred at the end of October. Therefore Jesus Christ's conception occurred at the end of April. Scripture indicates that Zacharias' course fell in the ninth week of the year before Pentecost. He remained for the Pentecost week. John the Baptist was conceived in mid to late June. Jesus Christ's conception occurred in December.