Abraham's calling marks the beginning of a profound spiritual journey, establishing him as a pivotal figure in the history of faith. God chose Abraham to be the father of a new spiritual race, a landmark in the spiritual history of the world. Through His divine selection, Abraham became a type of God the Father, uniquely representing Him in the biblical narrative. His natural abilities, combined with God's Spirit and his yieldedness through faith, enabled God to perform mighty spiritual works through him, making Abraham a singular figure in spiritual heritage. God called Abraham out of his country, kindred, and father's house, initiating a separation from his world with promises of blessing and greatness. This call, recorded in Genesis 12, was a rudimentary form of the gospel, showing that history is not aimless but directed by God's action to produce sons and heirs. Abraham responded with belief and obedience, though not without struggle, as he faced challenges in leaving his roots, moving from Ur to Haran and eventually to Canaan after his father Terah's death. This journey was not instantaneous; it involved a considerable entourage and logistical difficulties, reflecting the human challenges of following God's command. Abraham's life of faith was characterized by constant movement and instability, living as a stranger and pilgrim in tents, always reminded that he had no settled place. Despite entering his promised inheritance, he faced famine, warfare, and persecution, never leading a settled life even as he became wealthy. His path illustrates that a true son of Abraham will not have a simple life, often requiring painful sacrifices and learning through instability what lies in the heart. Central to Abraham's calling was his personal relationship with God, which he cherished above the land or reward. This relationship, marked by God's covenant and promises, motivated Abraham to move and live by faith, trusting in the character and power of the One who said, "I will." His unique designation as God's friend highlights this bond, a status not based on mere descent but on submitting to and trusting in God's word, producing the works of faith. For Abraham's spiritual descendants, being his seed is not about blood relation but being in Christ, requiring the same spirit of faith and obedience to God's call, separating from the world and prioritizing a relationship with Him through communication and trust.

Around 1902 BC, Abram, a man of princely birth with a Hebrew name, faced persecution from the Assyrians under Count Sattan. Defeated, he fled Mesopotamia, leaving his wife Suzanna and their newborn son Achaim behind, and sought refuge in the Danube Valley, an area with a significant Hebrew population descended from Eber through Joktan. After Count Sattan's death around 1898-1899 BC, Abram returned to Mesopotamia to reclaim his family, intending to settle back in the Danube River Valley, possibly referred to as the Jew's land in historical records. However, at this time, as recorded in Genesis 12, God had other plans for Abram, directing him southward instead of to the north and west. Abram, later known as Abraham, faced further persecution upon his return, likely from the same forces as before, including the Chaldean priesthood who opposed his teachings. Abraham taught the people of Mesopotamia that creation proved the existence of a Creator God, arguing against the Chaldean belief in heavenly bodies as gods by asserting that a greater power regulated their motions. This stance threatened the priesthood's control, leading to efforts to suppress his influence. Living in a time of widespread idolatry, even among his own family, Abraham stood out as the man God chose to rekindle the flame of truth. With little contact with other bearers of truth like Shem or Eber, he grew in understanding and faith over time, developing his character to become the father of the faithful. God appeared to him before he dwelt in Haran, and by age 75, when God commanded him to leave, Abraham was becoming familiar with God's guidance. His movement from Ur to Haran to Canaan involved a significant following, possibly including servants and persuaded followers, marking the beginning of a pilgrimage akin to a church on earth at that time. Abraham's call required immense sacrifice, relinquishing potential prestige, power, and wealth as a direct descendant in line to be patriarch over the Semitic peoples. This position carried great responsibility over many nations, chosen by God to model and reveal His truth. Submitting to God's will, Abraham obeyed when called to leave Mesopotamia, demonstrating profound trust in God's plan.